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KMID : 0379120030310020114
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Korean Journal of Mycology
2003 Volume.31 No. 2 p.114 ~ p.116
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Detection of Platelet Aggregation Inhibitors and Fibrinolytic Substances from Mushrooms
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Park Jung-Sik
Lee Jong-Soo
Jo Soo-Mook
Hyun Gwang-Wook
Seo Seung-Bo
You Chang-Hyun
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Abstract
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Platelet aggregation inhibitory and fibrinolytic activities of water and ethanol extracts from mushrooms were studied. The highest platelet aggregation inhibitory activity was 81.2% in the ethanol extract from fruiting body of Inonotus obliquus ASI 74006 and also were high in the ethanol extract from fruiting bodies of Fomitella fraxinea. The ethanol extract from the mycelia of Agaricus blazei Murill. ASI 1174 showed the strongest fibrinolytic activity as 9.6 unit. However fibrinolytic activities of other mushrooms were low or negligible.
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KEYWORD
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Fibrinolytic substances, Mushrooms, Platelet aggregation inhibitor
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